1) University Medicine Göttingen, Dept. for Diagnostic and Interventional Radiology; 2) MPI for Multidisciplinary Sciences Göttingen, Translational Molecular Imaging; 3) University Hospital Heidelberg, Dept. for Diagnostic and Interventional Radiology and Translational Lung Research Center, 4) Italian synchrotron “Elettra” Trieste, SYRMEP group
X-ray imaging techniques in heart and lung research
Host: L. Braga
Abstract:
Imaging has become indisputable not only for medical diagnosis, staging of diseases and following therapy response, but also in biomedical research. Since, the latter is usually con- ducted in small animal models, the smallness of the organs and the their rapid motion gen- erate strong challenges for the application of imaging techniques. X-ray imaging despite the known side-effects can offer great spatial and temporal resolution, but suffers from an intrinsic low contrast for soft-tissue.
The talk will summarizes the essential technical details of x-ray imaging, staining and contrast agent approaches as well as the special advantages of Synchrotron based x-ray imaging. Furthermore, I will present different applications for in-vivo and ex-vivo imaging
in heart and lung research, ranging from correlative virtual histology of formalin-fixed and paraffin-embedded tissue, in-vivo functional heart and lung imaging towards potential new imaging techniques for future patient applications.
Background:
I’m a physicist by training and lecturer in experimental radiology at the University Medicine Göttingen and a member of the German Lung Research Center in Heidelberg. Moreover, I’m a long term collaborator of the Italian synchrotron in Trieste. I have about 20 years experi- ence in preclinical imaging using mostly x-ray imaging techniques and I’m in charge of the preclinical imaging facility at the University Medicine Goettingen. Currently, I’m one of the Scientific Ambassadors of the European EuroBioImaging initiative.
International Seminar Programme
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