Katherine R. SABOURIN

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Assistant Professor of Epidemiology in the Department of Environmental

& Public Health Sciences, University of Cincinnati College of Medicine

Unraveling Kaposi sarcoma-associated herpesvirus (KSHV) reactivation and it’s potential relationship

with malaria

Host: G. Schafer

Abstract
Kaposi’s sarcoma (KS) remains a common cancer in people

living with HIV worldwide, particularly in sub-Saharan

Africa, where seroprevalence of KSHV, the causal agent

of KS, exceeds 90% in adults. Reactivation of KSHV in the

blood is a recognized risk factor for KS development, while

reactivation in saliva is required for transmission. Yet the

factors that drive reactivation remain poorly understood.

This talk will explore the potential role of malaria, a

co-infection common in many regions where KSHV is

endemic, in triggering KSHV reactivation, and what this

could mean for both KS risk and viral transmission.

International Seminar Programme

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Recapiti
Marella Prata