TG6050
TG6050 an innovative oncolytic virus from the Invir.IO® platform.
TG6050 has been engineered to express into the tumor, human IL-12, a cytokine that triggers a powerful antitumor immune response, and a full length anti-CTLA4 antibody.
Specifically multiply and induce tumor cell lysis (or oncolysis).
Derived from the Invir.IO® platform, our oncolytic viruses infect, specifically multiply and induce tumor cell lysis (or oncolysis).
These viruses also integrate anti-cancer weapons into their genome, enabling them to modulate the tumor microenvironment.
These different mechanisms lead to the destruction of tumor cells and the activation of the immune system, while preserving the patient’s own healthy cells.
Designed to induce a strong immune response against the tumor
Additional ressources
Last press releases
February 6, 2025
Transgene Shares (Euronext Paris: TNG) Eligible for Inclusion in PEA-PME Accounts
January 21, 2025
Transgene To Participate in the Biomed Forum Investor Conference
January 14, 2025
Transgene Announces Financial Calendar for 2025
August 27, 2024
Transgene — Preclinical Proof of Concept Data of Oncolytic Virus TG6050 published in JITC
May 10, 2023
Transgene – First Patient Dosed in Phase I Trial Evaluating TG6050, a Novel IL-12-Armed Oncolytic Virus Administrated Intravenously, in Non-Small Cell Lung Cancer
April 17, 2023
Transgene – Preclinical Results Showing TG6050, a Novel Oncolytic Virus, induces Tumor Regression by Activating Innate and Adaptive immune responses presented at AACR
March 15, 2023
Transgene to Present Multiple Posters Highlighting the Potential of its Exciting Immunotherapy Pipeline at AACR 2023
January 6, 2023
Transgene Receives Approval to Start a Phase I Trial of TG6050, a Novel IL-12-Armed Oncolytic Virus Given by Intravenous Administration
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